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Automation in Freeze-Drying

Automation in Freeze-Drying

In the last 25 years, the percentage of lyophilized products has increased from 10% to almost 30% of the existing parenteral drugs. In addition, 80% of the freeze-dried parenteral drugs are lyophilized in vials. Vials are the most standardized solution for freeze drying products, such as vaccines, peptides and proteins, due to the enormous advantages for transport and shelf life. The continuous development of new formulations and products of the pharmaceutical industry reques

Freeze drying Probiotics?

Freeze drying Probiotics?

The name probiotic comes from the Greek words pro bios meaning “for life”. Probiotics is known to give beneficial effect on human body such as improving intestinal motility, strengthening immunity, reducing atopic diseases and suppressing noxious germs. In the past, the general way to ingest probiotics were drinking liquids, though there is a limitation in terms of storage time and practical efficacy. Freeze drying technology opened a new way of consuming probiotics with high

12 steps of Lyophilization History you should know

12 steps of Lyophilization History you should know

The origins of freeze drying can be traced back to the 15th century, where a rudimentary form of freeze drying was used by the Incas. Freeze-drying became recognized as an important technique for the preservation of numerous biologicals after centuries. What is in one picture its evolution? LyophilizationWorld has developed the below timeline to comprehend freeze-drying past and present and be part of its future. #Freezedryer #Lyophilizationprocess

The 3 Challenges of integrating Filling line and Freeze Dryer

The 3 Challenges of integrating Filling line and Freeze Dryer

As the pharma industry evolved the need of automated and integrated lines (filling – freeze-dryer) grew worldwide. In the recent years close to 80% of the pharma freeze-dryers are connected through direct conveyor to the automatic loading system and filling line. After different steps (washing, sterilization etc.) a module fits the filled vials with a rubber stopper as a seal. The stopper is pushed in fully for liquid products but only part of the way for freeze-drying produc

The newest laboratory freeze dryer by ilshinbiobase

The newest laboratory freeze dryer by ilshinbiobase

Many people search for a freeze dryer and are surprised, even overwhelmed, with the number of choices available. The biggest question seems to arise when trying to determine the best laboratory freeze dryer: since “everything” begins at the lab. One of the most important factors in determining the right lyophilizer for your needs is the temperature its collector coil can reach. Lab freeze dryers cool anywhere from -50° C (-58° F) to -105° C (-157° F). Collector temperatures a

A giant from Korea – IlshinBioBase

A giant from Korea – IlshinBioBase

Improvements in the process of Freeze drying and of the equipment to carry it out have been a continuous challenge since this technology’s very beginnings. The design of units for efficient cycle under aseptic conditions has led to the development of specific equipment solutions for use in laboratory as well as in industrial applications. With more than 30 years of experience in this field, Ilshin has specialized in the design and production of GMP equipment for the industria

Why Emerging Markets? Why Emerging Freeze dryer Manufacturers?

Why Emerging Markets? Why Emerging Freeze dryer Manufacturers?

Few years ago, multinational pharma companies seeking growth and respite from market uncertainty in Europe and the United States found a haven in emerging markets. However, a more somber outlook soon replaced early euphoria. Some emerging markets either suffered downturns or showed weaker growth forecasts as commodity prices fell; some healthcare systems struggled to scale up adequately their provision of care; and local companies became increasingly effective competitors in

Side Maintenance Door or Back Maintenance Door in a Lyophilizer

Side Maintenance Door or Back Maintenance Door in a Lyophilizer

With integrated Automatic Loading System and/or due to room restrictions, the position of the lyophilizer maintenance door is a delicate matter. In another article we will detail the different LUS (loading/unloading system) in the market; for now, we should take into consideration that they will be front-sided LUS or front-back-sided: in other words they will “stress” one or two chamber wings. From a general point of view a one sided-LUS is able to release the mechanical pres

EU vs China made

EU vs China made

The BCG (Boston Consulting Group) stated in an article “For some machinery subsectors in Germany, the threat from Chinese challengers is already evident.In machinery subsectors in which the catch-up barriers are high and the catch-up capabilities of Chinese companies are low, European companies should nevertheless act to preserve their dominant position for as long as possible.” Freeze-dryer Manufacturer Factories Worldwide We can clearly see a trend in the manufacturing side

Interested in writing for Lyophilizationworld? We welcome reviews, news, items, and new product features relating to pharmaceuticals, industrial science and lyophilization.

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