The main effects of the frost buildup on the freeze dryer shelvesHumidity is an essential parameter to consider when we have pre-frozen products to be loaded into the freeze-dryer. These are the most impor
The 6 most challenging samples in lyophilization cycle developmentIn our previous article about QbD, it was mentioned that lyophilization has been considered an art, and cycles developed by trial and...
Reconstitution Time for Lyophilized products: overcome the challenges!A number of drugs are unstable in an aqueous environment, even when exposed for a short duration, thus requiring packaging, storage, and...
Isolators available on the MarketIsolators are routinely found within the pharmaceutical industry and are widely used in Europe (and increasingly in the US) for aseptic...
Overcome the distanceSeveral questions showed up after our previous post, here there is a more precise information about the different strategies and...
Side Maintenance Door or Back Maintenance Door in a LyophilizerWith integrated Automatic Loading System and/or due to room restrictions, the position of the lyophilizer maintenance door is a delicate...
Silicone Oil Leakage Detection in Freeze DryersAs a small leakage from the silicone oil tubes in pharmaceutical freeze dryers may go undetected for several cycles, it provides a major...
EU vs China madeThe BCG (Boston Consulting Group) stated in an article “For some machinery subsectors in Germany, the threat from Chinese challengers is...
Freeze Dryer MaintenanceAs is the case with all categories of pharmaceutical equipment, the maintenance of your freeze dryer depends on 3 HOWs: How you use it...
Miscomprehension about rubber stoppers in Freeze DryingLyophilization or Freeze-Drying is broadly used for pharmaceuticals to preserve parenteral drugs properties that are unstable in liquid...
