The Complexity and Beauty of Lyophilization
The lyophilization process primarily consists of three stages. The first stage is freezing, which involves freezing the product and...
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Common problems with lyophilized drugs in the lyophilization process
COLLAPSE Cause: It is a phenomenon which occurs in amorphous solids when the product reaches a higher temperature than the collapse...
Freeze-Drying Food
Freeze-drying is a very gentle dehydration process used for preservation of high quality foods. During the 1950s, industrial...
Upscaling with Teclen Lyoprotect® containers
The transfer of the recipe from laboratory scale to production scale is one of the biggest obstacles for manufacturers. Freeze drying is...
Using new chemicals in your freeze dryer?
Freeze driers are designed to be chemical resistant to most compounds that are commonly used in freezedrying processes. However, a freeze...
Lyophilizer Cleaning Validation: Why Perform Cleaning Validation?
The lyophilized drugs in the pharmaceutical industry cannot afford to compromise on cleanliness. Lyophilizer contamination results in...
How to audit a Freeze Dryer Supplier
In the last 25 years, the percentage of freeze-dried products has increased from 10% to almost 30% of the existing parenteral drugs. In...
The evolution of Freeze-Drying
THE FREEZE-DRYING TIMELINE Looking back to the timeline we see a substantial growth in the usage as well as the technology of freeze...
Corning Valor® Vials Demonstrate Superior Performance by Resisting Breakage During Low Temperature P
Glass vial failures, specifically breakage, lensing, and cracks, are a source of product loss and process cost in the freeze-thaw,...
Splashing? How to avoid it during vials filling process
Nowadays almost 50% of the injectable products that are in clinical trials or are approved for marketing, are freeze dried products. Main...
Why the cosmetic industry is interested in Freeze-Drying?
Innovation in sectors such as the makeup and skin care industry is being led by companies mainly located in Asia that are currently...
Pharmaceutical glass packaging innovation
Delamination has existed as a fundamental glass challenge for pharmaceutical manufacturers for decades. Delamination Explained While...
Dangerous volatile APIs?
Volatile API compounds are the most sensitive components in the process of drying. The effect of drying on the composition these products...
Automation in Freeze-Drying
In the last 25 years, the percentage of lyophilized products has increased from 10% to almost 30% of the existing parenteral drugs. In...
How to improve Safety in the production of Cancer Drugs
ProJect Pharmaceutics transforms all kinds of chemical and biological ingredients into pioneering drugs. They are experts in formulation...
Freeze drying Probiotics?
The name probiotic comes from the Greek words pro bios meaning “for life”. Probiotics is known to give beneficial effect on human body...
Interview with Richard Denk
Have you ever joined Richard Denk in a PDA Chapter? LyophiliationWorld is glad to propose an interview with the most reputable expert in...
The Rising of a player: i-Dositecno
The number of parenteral products entering development and reaching the market has increased significantly during the past decade. By...
Heraeus Relies on Teclen® Lyoprotect® for the Process Development and Manufacturing of Toxic Substan
The Heraeus Pharmaceutical Ingredients Business Line Within the globally active Global Business Unit Heraeus Precious Metals, the...
12 steps of Lyophilization History you should know
The origins of freeze drying can be traced back to the 15th century, where a rudimentary form of freeze drying was used by the Incas....
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