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LyoCLC® – Predictive Modeling of the Primary Drying Endpoint in Pharmaceutical Freeze-Drying
Scientific Process Optimization through Real-Time Monitoring and Data-Driven Control In pharmaceutical manufacturing, freeze-drying...
Heat Transfer Modes During Lyophilization Process
Considering the lyophilization of vials, three different modes of heat transfer occur during the Freeze-Drying process: ✓ Conduction...
Computational simulation tools in Lyophilization
Building a designs pace for a freeze drying process has classically required extensive experimental runs, that can be long in time...
What temperature will my product be at during the primary drying step?
The drying energy is proportional to the temperature difference between the shelf (Tf) and the phase change temperature of pure ice at...
Lyophilization Cycle Scale-Up and Transfer
Lyophilization Cycle Scale-Up and Transfer require reproducing the initial product temperature profile onto the target freeze-dryer. By...
Accelerate your LyoProcess Development. Get it Right the First Time
Make your Work Easier Enhance your laboratory freeze-dryer with cutting edge measurement technology combined with a novel method for...
How Thermodynamics applies to Lyophilization?
1. Phase Changes : - Lyophilization involves several phase changes, primarily the transition from liquid to solid (freezing) and then...
Speed Up Drug Approval: How Tempris Revolutionizes Lyophilized Drug Approval
Every pharmaceutical product demands precise process parameters to ensure quality throughout its shelf life. The FDA report "A Regulatory...
Lyophilization: eliminating the need for cold chain logistics
Lyophilization, also known as freeze-drying, is a process being increasingly adopted by in vitro (IVD) assay developers looking to...
How are Lyo beads manufactured?
To download this process infographic, click here Lyo beads are durable spheres of freeze-dried material formed from accurately measured...
Lyophilization Cycle Scale-Up and Transfer
Lyophilization Cycle Scale-Up and Transfer require reproducing the initial product temperature profile onto the target freeze-dryer. By...
Can Lyophilized beads increase assay accuracy?
What are Lyophilized beads? Lyophilized beads are durable spheres of freeze-dried material formed from accurately measured volumes of...
Lyophillizer Validations, Aseptic Process simulations design-Lyo process and Rationale for Hold duration of Partially Stoppered Media Filled Vials-In compliance with Revised EU Annex-1 2022 (part II)
Author: Varadharaj Vijayakumar - Aseptic Technology, Isolators & Lyophilization Following our previous article part I, the purpose of...
Lyophillizer Validations, Aseptic Process simulations design-Lyo process and Rationale for Hold duration of Partially Stoppered Media Filled Vials-In compliance with Revised EU Annex-1 2022 (part I)
Author: Varadharaj Vijayakumar - Aseptic Technology, Isolators & Lyophilization After two draft documents from 2017 and 2020, more than...
Cryopreservation vs. Lyophilization: Decoding the glass transition phenomenon
In the realm of preserving delicate biological substances and pharmaceuticals, two prominent methods take centre stage: cryopreservation...
Freeze Drying: Facts vs. Fiction
Introduction Freeze drying, also known as lyophilization, is a vital process in the production of many pharmaceuticals, diagnostics, and...
Stability to probiotic cultures and functional foods ingredients
There is accumulating clinical data supporting the role of probiotics in human health particularly in benefiting the immune system,...
How To Ensure Your API Is Compatible With Its Formulation
Years of hard work and research go into developing new APIs, so when it comes to developing one into a new formulation for mass...
Freeze Drying Process Steps
Freeze drying is а three step linear process: Freezing, Primary Drying, and Secondary drying. Each step is outlined below. Freezing The...
How freeze drying optimises the processing and viability of collagen bio-scaffolds
Collagen bio-scaffolds are hugely beneficial to many medical fields and therefore it is essential that the process used to develop them...
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