Freeze Drying vs Spray Drying – Which is Most Suitable For Your Projects?
The demand for productivity and profitability in the freeze drying, also known as lyophilisation, sector is increasing. This increase is...
top of page
Search
Solution for Freeze-Dried ODTs
Orally disintegrating tablets (ODTs) is fast-dissolve formulation. The unique, freeze-dried oral solid dosage form disperses almost...
High-speed Vaccine Filling and Packaging Technologies
In the pharmaceutical industry, high-speed vial filling and packaging has always been a problem, especially during mass production. While...
Freeze Drying System in API Production
Active Pharmaceutical Ingredient (API) is defined as a kind of active ingredient obtained by chemical synthesis, semi-synthesis,...
The Challenges of Spray Drying, the Alternative to Lyophilization
With a longer history of use, freeze-drying presents a plethora of fundamentally important research works on the mechanism behind...
Finished Product Testing For Lyophilized Products
There are several aspects of finished product testing which are of concern to the lyophilized dosage form. These include dose uniformity...
Thinking of the Development Trend of Sterile Freeze-dried Injection
On February 20, 2020 the Directorate for Health and Food Safety of the European Commission published a further draft for the revision of...
Why Perform Batch Control the Freeze Drying Process
Why Perform Batch Control of the Freeze Drying Process? Almost half of all biological products produced within the pharmaceutical...
PCR Diagnostic Kits & Freeze-Drying Considerations
PCR Process Overview Polymerase chain reaction (PCR) is a method widely used in molecular biology to make many copies of a specific DNA...
Inspection of Lyophilized Products: Container Closure Integrity (part 5)
Commonly referred to also as "Leak Control/Testing" or "Integrity Test", the CCIT (Container Closure Integrity Testing) is intended to...
Organic Solvent Recovery
Recovery of solvents from process streams is necessary, from both ecological and economical points of view. The goal is to recover,...
Considerations for Freeze-Drying in Dual Chamber Package Systems
Many parenterals, especially biotherapeutics, are unstable in aqueousbased formulations for long periods of time and are, therefore,...
Minimizing Aseptic Pharmaceutical Manufacturing Risks with the Inclusion of Depyrogenation Tunnels
Introduction Regulatory agencies prefer injectable products to be terminally sterilized. For some products, such as biological drugs,...
Freezing and Annealing Phenomena in Lyophilization
The freezing step of lyophilization is of paramount importance. It is the principal dehydration step, and it determines the morphology...
Inspection of Lyophilized Products: From Regulations to Implementation and Production (part 4)
We have discussed in previous part 3 the main regulations and requirements about visual inspection covered by USP, EP and JP...
Ensure the Efficiency and Safety of Your Freeze Drying Process
Freeze drying is a critical process for producing biological drugs in vials within the pharmaceutical industry. The FDA estimates that...
Tackling the challenges of small batch manufacturing in fill-finish programs
The biopharmaceutical industry continues to grow rapidly, driven by more specialized treatment protocols and the development of new and...
Molded vial manufacturing and its impact on heat transfer during freeze-drying
Glass vials are the most common primary packaging material used in pharmaceutical freeze-drying. Depending on the manufacturing process,...
Inspection of Lyophilized Products: Defect Prevention vs Removal - QA vs QC (part 3)
According to ISO 9001:2015, quality is: “the degree to which a set of inherent characteristics of an object fulfill requirements”....
The Air Cycle Refrigeration Revolution in Lyophilization - MIRAI COLD 80 T
Mirai Intex is proud to introduce the most powerful refrigeration machine added to their product portfolio. Same as the rest of their...
Interested in writing for Lyophilizationworld? We welcome reviews, news, items, and new product features relating to pharmaceuticals, industrial science and lyophilization.
Please email us with your suggestion or for further details.
bottom of page