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Glass vial failures, specifically breakage, lensing, and cracks, are a source of product loss and process cost in the freeze-thaw, cryogenic preservation, and lyophilization of pharmaceutical products. Lyophilization is a common method for the preparation of freeze-dri...

Delamination has existed as a fundamental glass challenge for pharmaceutical manufacturers for decades. 

Delamination Explained

While boron, a volatile element, is the root cause for delamination – the converting process also impacts a container’s chemical durability. Du...

As well as our article on Rubber Stoppers having a big influence on the performance during freeze drying, selecting the right Glass Vial can also improve the efficiency of your freeze-drying cycle and the lyophilization cake.

What can be advisable is to check with a sup...

How to solve contamination issues in freeze dryers with an existing recipe? Teclen can protect your lyo products as well as the operator through a unique technology...

Many biotechnologically manufactured substances are not sufficiently stable in aqueous solutions. Because of this, liquid formulations are quite difficult or in some cases, merely impossible to preserve for longer periods. One solution, however, is freeze-drying, by wh...

A number of drugs are unstable in an aqueous environment, even when exposed for a short duration, thus requiring packaging, storage, and shipping in a powder or lyophilized state to keep the product stable during its shelf life. Used for parenteral administration, thes...

Lyophilization or Freeze-Drying is broadly used for pharmaceuticals to preserve parenteral drugs properties that are unstable in liquid formulation. Lyophilized drugs have many advantages like prolonged shelf life, easy reconstitution and good stability. Therefore, the...

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