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In the last 25 years, the percentage of lyophilized products has increased from 10% to almost 30% of the existing parenteral drugs. In addition, 80% of the freeze-dried parenteral drugs are lyophilized in vials. Vials are the most standardized solution for freeze dryin...

The name probiotic comes from the Greek words pro bios meaning “for life”.

Probiotics is known to give beneficial effect on human body such as improving intestinal motility, strengthening immunity, reducing atopic diseases and suppressing noxious germs.

In the past, the...

The origins of freeze drying can be traced back to the 15th century, where a rudimentary form of freeze drying was used by the Incas. Freeze-drying became recognized as an important technique for the preservation of numerous biologicals after centuries. What is in one...

As the pharma industry evolved the need of automated and integrated lines (filling – freeze-dryer) grew worldwide. In the recent years close to 80% of the pharma freeze-dryers are connected through direct conveyor to the automatic loading system and filling line.

After...

Many people search for a freeze dryer and are surprised, even overwhelmed, with the number of choices available. The biggest question seems to arise when trying to determine the best laboratory freeze dryer: since “everything” begins at the lab.

One of the most importan...

Improvements in the process of Freeze drying and of the equipment to carry it out have been a continuous challenge since this technology’s very beginnings. The design of units for efficient cycle under aseptic conditions has led to the development of specific equipment...

Few years ago, multinational pharma companies seeking growth and respite from market uncertainty in Europe and the United States found a haven in emerging markets. However, a more somber outlook soon replaced early euphoria. Some emerging markets either suffered downtu...

With integrated Automatic Loading System and/or due to room restrictions, the position of the lyophilizer maintenance door is a delicate matter.

In another article we will detail the different LUS (loading/unloading system) in the market; for now, we should take into co...

As a small leakage from the silicone oil tubes in pharmaceutical freeze dryers may go undetected for several cycles, it provides a major threat to both product safety and the economic performance of the installations.


Product losses due to coolant contamination in free...

The BCG (Boston Consulting Group) stated in an article “For some machinery subsectors in Germany, the threat from Chinese challengers is already evident.In machinery subsectors in which the catch-up barriers are high and the catch-up capabilities of Chinese companies a...

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